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Ketoconazole 2% shampoo used as a body wash 2-3 times weekly can clear yeast-related bumps within 2-4 weeks, but will have zero effect on true comedones

However, other strategies are showing promise, particularly antisense oligo and antibody-based approaches

Conversely, inhibiting TLR4 can suppress microglial activation, alleviate neuroinflammation, improve cognitive function, and mitigate synaptic plasticity impairments and depression-like symptoms via this pathway (159, 160)